Wholesome in bulk™ Grape Seed Extract Powder
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Bulk Grape Seed Extract Powder for Supplement Manufacturing
Grape seed extract is a dry powder made from the seeds of wine grapes, Vitis vinifera L., extracted with water or ethanol and then dried. It is usually standardized to proanthocyanidins, often called OPCs, measured by UV or HPLC. We supply it in bulk to supplement brands, contract manufacturers, and formulators. You can request testing documents and samples on the quote form.
A seed extract with a measurable marker class
Grape seed extract is specified by its proanthocyanidin content. A USP monograph sets out identity tests and assay methods, so your quality team has a public reference to work from. Pin down the grade, the assay method, and the solvent for each lot.
Proanthocyanidins as the marker
Proanthocyanidins are chains of catechin and epicatechin units found in grape seed. Short chains of two to five units are called oligomeric proanthocyanidins, or OPCs.
Two common assay methods
Most bulk listings state OPC content by UV, a spectrophotometric method. The USP monograph measures oligomers by HPLC and sets a minimum of 75.0%, so the two numbers are not directly comparable.
Identity by fingerprint
The USP identity test is an HPTLC fingerprint that shows dimer, trimer, and epicatechin gallate bands. Matching that pattern against a reference standard confirms grape seed as the source.
Familiar market grades
The most widely listed grade is 95% OPC by UV. Suppliers also sell 95% polyphenol grades and grades up to 98% OPC, so match the grade name to the method on the COA.
Fine, water soluble powder
Grape seed extract is a fine reddish brown to dark brown powder that dissolves in water. Most spec sheets call for 95% through an 80 mesh screen, which suits capsule filling and dry blending.
Water and ethanol extraction
Seeds are extracted with hot water, ethanol, or a mix of the two, then purified and dried. Some processes use other solvents, so ask which solvent your lot used.
Where formulators use grape seed extract
This extract fits measured formats where fill weight and serving size are controlled, including:
- Capsules
- Compressed tablets
- Single ingredient powders
- Multiple ingredient botanical blends
- Stick packs and sachets
- Powdered drink mixes, after taste trials
- Functional beverages, after color and taste trials
- Gummies, after taste and stability trials
- Private label programs
Grape seed extract has a bitter, astringent taste and gives water a dark reddish brown color. Plan taste and color trials for drinks and gummies, and base fill weights on the confirmed assay on each COA.
What to check before you buy grape seed extract
Two powders sold as 95% OPC can differ in source, assay method, and solvent. Review these points together, and ask for lot documents before you approve a supplier.
Species and plant part
Confirm Vitis vinifera L. seed on both the specification and the certificate of analysis (COA). Grape pomace extract, which includes skins, is a different ingredient with a different profile.
Assay method and basis
Ask whether the OPC figure comes from UV, HPLC, or another method, and whether it is on a dry or as is basis. A total polyphenol result by Folin-Ciocalteu is a different measure again.
Identity fingerprint
Ask for an HPTLC or HPLC fingerprint compared with a grape seed reference standard. Peanut skin and pine bark carry similar compounds, so a fingerprint is the reliable way to confirm the source.
Allergen statement
Ask for a written allergen statement that covers peanut. Keep it in your supplier file with the identity data for the same lot.
Solvent and carrier
Confirm the extraction solvent and the residual solvent result. Ask whether any carrier, such as maltodextrin, is added to reach the stated grade.
Contaminant limits
Check heavy metals by ICP-MS, microbial limits by USP methods, and pesticide residues. Compare each limit with your own finished product specification.
Label math: If your label lists proanthocyanidins per serving, base the number on each lot's measured assay and your own finished product testing. Note the method too, because a UV result and an HPLC result for the same powder are different numbers.
Typical specification for grape seed extract
These values reflect the common 95% OPC grade by UV, with USP monograph limits shown for comparison. Final figures come from the specification sheet and COA for your lot. NLT means not less than, and NMT means not more than.
| Parameter | Specification | Method |
|---|---|---|
| Botanical source | Vitis vinifera L., seed | HPTLC fingerprint |
| Appearance | Fine reddish brown to dark brown powder | Visual |
| Proanthocyanidins (OPC) | NLT 95% | UV |
| Oligomeric proanthocyanidins, USP basis | NLT 75.0%, anhydrous, if tested to USP | HPLC (USP monograph) |
| Catechin plus epicatechin | NMT 19.0% | HPLC (USP monograph) |
| Extraction solvent | Water and ethanol | Supplier declaration |
| Carrier | None, or as named on the specification sheet | Supplier declaration |
| Particle size | NLT 95% through 80 mesh | USP <786> |
| Loss on drying | NMT 5.0% | USP <731> |
| Total ash | NMT 5.0% | USP <561> |
| Lead | NMT 2.0 ppm | ICP-MS |
| Arsenic | NMT 1.0 ppm | ICP-MS |
| Cadmium | NMT 1.0 ppm | ICP-MS |
| Mercury | NMT 0.5 ppm | ICP-MS |
| Residual solvents | Meets USP <467> | GC |
| Pesticide residues | Meets USP <561> | GC-MS and LC-MS |
| Total aerobic count | NMT 10,000 cfu/g | USP <2021> |
| Yeast and mold | NMT 1,000 cfu/g | USP <2021> |
| E. coli and Salmonella | Negative in 10 g and 25 g | USP <2022> |
| Shelf life | 36 to 60 months, unopened | Stability data |
Storage and handling for bulk grape seed extract
Seed extracts keep best when they stay sealed, dry, and out of light. These steps keep the powder in good condition between production runs.
Keep it sealed
Close the inner liner after each use and press out the air. The powder picks up moisture from the air and can cake when left open.
Store cool and dry
Keep bags off the floor in a dry room at controlled room temperature. Follow the range on the spec sheet.
Keep away from light
Leave the powder in its original opaque packaging. The USP monograph calls for storage away from light and moisture.
Rotate stock
Record the lot number and retest date for each bag. Send older lots to production first.
Grape seed extract buyer FAQ
Quick answers to the questions procurement and quality teams ask most.
What does 95% OPC mean on grape seed extract?
It means the assay for that lot found not less than 95% proanthocyanidins, usually by a UV method. Check which method the COA names, because the figure depends on it.
Is a 95% UV grade the same as a USP grade?
No. The USP monograph measures oligomeric proanthocyanidins by HPLC and sets a minimum of 75.0% on an anhydrous basis. A UV method reads a broader group of compounds, so the two results are not directly comparable.
How do you confirm grape seed identity?
A chromatographic fingerprint compared with a reference standard confirms the source. HPTLC is the USP identity test, and LC-MS can pick up the A-type proanthocyanidins typical of peanut skin.
Is grape seed extract water soluble?
Yes, grape seed extract dissolves in water. The USP monograph allows NMT 2% water insoluble matter. Expect a dark reddish brown color and an astringent taste in drinks.
What documents can I get with an order?
A certificate of analysis (COA) and a specification sheet ship with every order. An allergen statement and a safety data sheet may also be available, depending on the lot in inventory. Contact us to request them.
Can I get a sample before a bulk order?
You can request one by choosing sample options on the quote form. We will confirm availability, size, and timing.
How should I store an opened bag?
Close the liner, press out the air, and keep the bag in a cool, dry place away from light. Use the powder within the shelf life shown on the COA.
Request a quote for bulk grape seed extract
Tell us your grade, assay method, quantity, and timing. We will reply with current pricing. Select testing documents and sample options on the quote form.
Order Grape Seed ExtractBulk orders: Choose a pack size above, or use the quote form for larger volumes, testing documents, and sample options. We serve supplement brands, contract manufacturers, product developers, and formulators.
This bulk ingredient is sold for further manufacturing and formulation. The information on this page describes the ingredient and how commercial buyers evaluate it. It is not medical advice. Each finished product brand is responsible for its own labeling and product claims.
