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Product Wholesome in bulk™ Calcium HMB Powder (Ca-HMB Monohydrate)
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Bulk Calcium HMB Powder for Supplement Manufacturing

Calcium HMB is a white to off white powder made from beta-hydroxy-beta-methylbutyrate (HMB) and calcium, usually supplied as the monohydrate salt. It is about 80 to 85% HMB by weight, depending on whether its bound water is counted. We supply it in bulk to supplement brands, contract manufacturers, and formulators. You can request testing documents and samples on the quote form.

Chemical name Calcium beta-hydroxy-beta-methylbutyrate monohydrate (Ca-HMB)
CAS number 135236-72-5
HMB content NLT 84.0% (HPLC), basis stated on the COA
Pack sizes 5 lb, 11 lb, 25 lb, and 55 lb
Why Calcium HMB

A dry, flowable salt with two assays on one COA

Calcium HMB turns an acid that is liquid at room temperature into a powder you can weigh, blend, and fill. Its HMB and calcium contents are both measurable, so quality teams can compare lots line by line.

Powder form of HMB

HMB in its free acid form is generally a liquid. The calcium salt is a dry powder, which suits capsules, tablets, and dry blends.

Known composition

Calcium HMB monohydrate has a formula weight of about 292. By weight that is roughly 80% HMB, 14% calcium, and 6% bound water.

Two assays on one COA

Good certificates of analysis (COAs) report calcium HMB and HMB by HPLC, and calcium by ICP-MS. Together they show that the salt ratio is right.

Water you can account for

The monohydrate carries bound water, so published specs allow loss on drying up to 7.0%. The COA should say whether the HMB result is on a dry or as is basis.

Powder and granular grades

Standard grades are fine powders with a bulk density of about 0.3 to 0.6 g/mL. Granular, encapsulated grades are also traded for formats that need better flow.

Clear identity on paper

Calcium HMB has its own CAS number, 135236-72-5. Suppliers publish batch COAs and safety data sheets, which makes supplier approval faster.

Formulation Uses

Where formulators use calcium HMB

This salt fits measured formats where fill weight and serving size are controlled, including:

  • Capsules
  • Compressed tablets
  • Single ingredient powders
  • Sports nutrition powders
  • Protein powders
  • Powdered drink mixes
  • Stick packs and sachets
  • Private label programs

Plan fill weights from the HMB result on each COA, not from the salt weight. At about 80% HMB as supplied, roughly 1,250 mg of calcium HMB monohydrate supplies 1,000 mg of HMB.

What Commercial Buyers Should Review

What to check before you buy calcium HMB

Powders sold as HMB can differ in salt form, hydrate, and how results are reported. Review these points together, and ask for lot documents before you approve a supplier.

Salt form and hydrate

Confirm calcium HMB monohydrate, CAS 135236-72-5, on both the specification and the COA. HMB free acid and other HMB forms carry different HMB content.

HMB assay and basis

Ask for HMB by HPLC and whether the result is on a dry or as is basis. A dry basis figure runs about five points higher than the as supplied figure for the same lot.

Calcium content

Calculated calcium is about 13.7% as supplied and 14.6% on a dry basis. Ask how calcium is measured, and ask the supplier to explain a result well outside that range.

Loss on drying

The monohydrate holds about 6% bound water. Compare the loss on drying result with that figure, and ask about any large gap.

Contaminant limits

Check heavy metals by ICP-MS and microbial limits by USP methods. Compare each limit with your own finished product specification.

Origin and supplier file

Ask for the country of manufacture and the producing plant. Published COAs list China, so a named site makes your supplier approval faster.

Label math: If your label lists HMB per serving, base it on the HMB assay and basis on each COA. Do not use the weight of the salt. One gram of calcium HMB monohydrate supplies about 800 mg of HMB as supplied. Ask your regulatory reviewer whether your panel also needs a calcium line.

Specification

Typical specification for calcium HMB

These values reflect common published specifications for calcium HMB monohydrate. Final figures come from the specification sheet and COA for your lot. NLT means not less than, and NMT means not more than.

Parameter Specification Method
Identity Calcium beta-hydroxy-beta-methylbutyrate monohydrate, CAS 135236-72-5 HPLC retention time against reference standard
Appearance White to off white powder Visual
Assay (calcium HMB) NLT 99.0% HPLC
HMB NLT 84.0%, basis stated on the COA HPLC
Calcium 13.5 to 14.5% ICP-MS
Loss on drying NMT 7.0% USP <731>
Particle size Stated on the COA USP <786>
Bulk density 0.3 to 0.6 g/mL USP <616>
Residual solvents Meets USP <467> GC, USP <467>
Lead NMT 3.0 ppm ICP-MS
Arsenic NMT 1.0 ppm ICP-MS
Cadmium NMT 1.0 ppm ICP-MS
Mercury NMT 0.1 ppm ICP-MS
Microbial limits Total aerobic count, yeast and mold, E. coli, and Salmonella limits stated on the COA USP <2021> and <2022>
Shelf life Shelf life and storage temperature from spec sheet Stability data
Storage & Handling

Storage and handling for bulk calcium HMB

Calcium HMB keeps well when it stays sealed, cool, and dry. Plan for dust control too, since fine powder becomes airborne during weighing.

Keep it sealed

Close the inner liner after each use and press out the air. A sealed bag holds the water content close to the figure on the COA.

Store cool and dry

Keep bags off the floor in a cool, dry room away from direct sunlight. Follow the temperature range on the spec sheet.

Control dust

Supplier safety data sheets classify calcium HMB dust as a skin, eye, and respiratory irritant. Use dust extraction, gloves, and eye protection when you weigh and blend.

Rotate stock

Record the lot number and retest date for each bag. Send older lots to production first.

Buyer FAQ

Calcium HMB buyer FAQ

Quick answers to the questions procurement and quality teams ask most.

How much HMB is in calcium HMB?

Calcium HMB monohydrate is about 80% HMB by weight as supplied, and about 85% on a dry basis. The rest is calcium (about 14%) and bound water (about 6%). Published specs often state NLT 84% HMB, so check which basis your COA uses.

Why do calcium HMB labels show different HMB amounts?

Labels differ when one counts the whole salt as HMB and another counts only the HMB part. For 1 g of calcium HMB, labels on the market list from about 825 mg to 950 mg of HMB. Work from the HMB assay and basis on your COA, and have your regulatory team review the panel.

What is the difference between calcium HMB and HMB free acid?

Calcium HMB is a dry calcium salt, while HMB free acid is the acid itself and is generally a liquid. The free acid is sold in gelcaps, and calcium HMB suits powders, capsules, and tablets. This page covers calcium HMB.

Should I choose a fine powder or a granular grade?

Choose a fine powder for drink mixes and dry blends. Ask about granular grades if your tablet press or capsule filler needs better flow.

What documents can I get with an order?

A certificate of analysis (COA) and a specification sheet ship with every order. An allergen statement and a safety data sheet may also be available, depending on the lot in inventory. Contact us to request them.

Can I get a sample before a bulk order?

You can request one by choosing sample options on the quote form. We will confirm availability, size, and timing.

How should I store an opened bag?

Close the liner, press out the air, and keep the bag in a cool, dry place away from direct sunlight. Use the powder within the shelf life shown on the COA.

Bulk Calcium HMB

Request a quote for bulk calcium HMB

Tell us your grade, quantity, and timing. We will reply with current pricing. Select testing documents and sample options on the quote form.

Order Calcium HMB

Bulk orders: Choose a pack size above, or use the quote form for larger volumes, testing documents, and sample options. We serve supplement brands, contract manufacturers, product developers, and formulators.

This bulk ingredient is sold for further manufacturing and formulation. The information on this page describes the ingredient and how commercial buyers evaluate it. It is not medical advice. Each finished product brand is responsible for its own labeling and product claims.

*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.